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Neurotrophin-mediated dendrite-to-nucleus signaling revealed by microfluidic compartmentalization of dendrites

Signaling from dendritic synapses to the nucleus regulates important aspects of neuronal function, including synaptic plasticity. The neurotrophin brain-derived neurotrophic factor (BDNF) can induce long-lasting strengthening of synapses in vivo and this effect is dependent on transcription. However...

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Bibliographic Details
Main Authors: Cohen, Michael S., Orth, Carlos Bas, Kim, Hyung Joon, Jeon, Noo Li, Jaffrey, Samie R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131323/
https://ncbi.nlm.nih.gov/pubmed/21690335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012401108
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