Pathologic and Phenotypic Alterations in a Mouse Expressing a Connexin47 Missense Mutation That Causes Pelizaeus-Merzbacher–Like Disease in Humans

Gap junction channels are intercellular conduits that allow diffusional exchange of ions, second messengers, and metabolites. Human oligodendrocytes express the gap junction protein connexin47 (Cx47), which is encoded by the GJC2 gene. The autosomal recessive mutation hCx47M283T causes Pelizaeus-Mer...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tress, Oliver, Maglione, Marta, Zlomuzica, Armin, May, Dennis, Dicke, Nikolai, Degen, Joachim, Dere, Ekrem, Kettenmann, Helmut, Hartmann, Dieter, Willecke, Klaus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131295/
https://ncbi.nlm.nih.gov/pubmed/21750683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002146
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