NatF Contributes to an Evolutionary Shift in Protein N-Terminal Acetylation and Is Important for Normal Chromosome Segregation

N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification. Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher eukaryotes, but evidence explaining the underlying molecular mechanism(s) is currently lacking. We first analysed protein N-te...

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Main Authors: Van Damme, Petra, Hole, Kristine, Pimenta-Marques, Ana, Helsens, Kenny, Vandekerckhove, Joël, Martinho, Rui G., Gevaert, Kris, Arnesen, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131286/
https://ncbi.nlm.nih.gov/pubmed/21750686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002169
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