Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB as Novel Risk Loci for Systemic Sclerosis

Systemic sclerosis (SSc) is an orphan, complex, inflammatory disease affecting the immune system and connective tissue. SSc stands out as a severely incapacitating and life-threatening inflammatory rheumatic disease, with a largely unknown pathogenesis. We have designed a two-stage genome-wide assoc...

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Autors principals: Allanore, Yannick, Saad, Mohamad, Dieudé, Philippe, Avouac, Jérôme, Distler, Jorg H. W., Amouyel, Philippe, Matucci-Cerinic, Marco, Riemekasten, Gabriella, Airo, Paolo, Melchers, Inga, Hachulla, Eric, Cusi, Daniele, Wichmann, H.-Erich, Wipff, Julien, Lambert, Jean-Charles, Hunzelmann, Nicolas, Tiev, Kiet, Caramaschi, Paola, Diot, Elisabeth, Kowal-Bielecka, Otylia, Valentini, Gabriele, Mouthon, Luc, Czirják, László, Damjanov, Nemanja, Salvi, Erika, Conti, Costanza, Müller, Martina, Müller-Ladner, Ulf, Riccieri, Valeria, Ruiz, Barbara, Cracowski, Jean-Luc, Letenneur, Luc, Dupuy, Anne Marie, Meyer, Oliver, Kahan, André, Munnich, Arnold, Boileau, Catherine, Martinez, Maria
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131285/
https://ncbi.nlm.nih.gov/pubmed/21750679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002091
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