Genome-Wide Scan Identifies TNIP1, PSORS1C1, and RHOB as Novel Risk Loci for Systemic Sclerosis

Systemic sclerosis (SSc) is an orphan, complex, inflammatory disease affecting the immune system and connective tissue. SSc stands out as a severely incapacitating and life-threatening inflammatory rheumatic disease, with a largely unknown pathogenesis. We have designed a two-stage genome-wide assoc...

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Autori principali: Allanore, Yannick, Saad, Mohamad, Dieudé, Philippe, Avouac, Jérôme, Distler, Jorg H. W., Amouyel, Philippe, Matucci-Cerinic, Marco, Riemekasten, Gabriella, Airo, Paolo, Melchers, Inga, Hachulla, Eric, Cusi, Daniele, Wichmann, H.-Erich, Wipff, Julien, Lambert, Jean-Charles, Hunzelmann, Nicolas, Tiev, Kiet, Caramaschi, Paola, Diot, Elisabeth, Kowal-Bielecka, Otylia, Valentini, Gabriele, Mouthon, Luc, Czirják, László, Damjanov, Nemanja, Salvi, Erika, Conti, Costanza, Müller, Martina, Müller-Ladner, Ulf, Riccieri, Valeria, Ruiz, Barbara, Cracowski, Jean-Luc, Letenneur, Luc, Dupuy, Anne Marie, Meyer, Oliver, Kahan, André, Munnich, Arnold, Boileau, Catherine, Martinez, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131285/
https://ncbi.nlm.nih.gov/pubmed/21750679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002091
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