FGF15/19 Regulates Hepatic Glucose Metabolism By Inhibiting the CREB-PGC-1α Pathway

Regulation of hepatic carbohydrate homeostasis is crucial for maintaining energy balance in the face of fluctuating nutrient availability. Here, we show that the hormone fibroblast growth factor 15/19 (FGF15/19), which is released postprandially from the small intestine, inhibits hepatic gluconeogen...

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Autori principali: Potthoff, Matthew J., Boney-Montoya, Jamie, Choi, Mihwa, He, Tianteng, Sunny, Nishanth E., Satapati, Santhosh, Suino-Powell, Kelly, Xu, H. Eric, Gerard, Robert D., Finck, Brian N., Burgess, Shawn C., Mangelsdorf, David J., Kliewer, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131185/
https://ncbi.nlm.nih.gov/pubmed/21641554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.03.019
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