The E3 Ubiquitin Ligase Cullin 4A Regulates Meiotic Progression in Mouse Spermatogenesis

The Cullin-RING ubiquitin-ligase CRL4 controls cell cycle, DNA damage checkpoint response and ensures genomic integrity. Inactivation of the Cul4 component of the CRL4 E3 ligase complex in Caenorhabditis elegans by RNA interference results in massive mitotic DNA re-replication in the blast cells, la...

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Main Authors: Yin, Yan, Lin, Congxing, Kim, Sung Tae, Roig, Ignasi, Chen, Hong, Liu, Liren, Veith, George Michael, Jin, Ramon U., Keeney, Scott, Jasin, Maria, Moley, Kelle, Zhou, Pengbo, Ma, Liang
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130830/
https://ncbi.nlm.nih.gov/pubmed/21624359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.05.661
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