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Pathogenicity of exonic indels in fused in sarcoma in amyotrophic lateral sclerosis

Insertion and deletion variants (indels) within poly glycine tracts of fused in sarcoma (FUS) were initially reported as causative of disease in amyotrophic lateral sclerosis (ALS). Subsequent studies identified similar indels in controls and suggested that these indels may confer susceptibility to...

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Detalhes bibliográficos
Main Authors: Rutherford, Nicola J., Finch, NiCole A., DeJesus-Hernandez, Mariely, Crook, Richard J.P., Lomen-Hoerth, Catherine, Wszolek, Zbigniew K., Uitti, Ryan J., Graff-Radford, Neill R., Rademakers, Rosa
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130814/
https://ncbi.nlm.nih.gov/pubmed/21074900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.09.029
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