Noninvasive Prenatal Diagnosis of Fetal Trisomy 18 and Trisomy 13 by Maternal Plasma DNA Sequencing

Massively parallel sequencing of DNA molecules in the plasma of pregnant women has been shown to allow accurate and noninvasive prenatal detection of fetal trisomy 21. However, whether the sequencing approach is as accurate for the noninvasive prenatal diagnosis of trisomy 13 and 18 is unclear due t...

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Detalhes bibliográficos
Main Authors: Chen, Eric Z., Chiu, Rossa W. K., Sun, Hao, Akolekar, Ranjit, Chan, K. C. Allen, Leung, Tak Y., Jiang, Peiyong, Zheng, Yama W. L., Lun, Fiona M. F., Chan, Lisa Y. S., Jin, Yongjie, Go, Attie T. J. I., Lau, Elizabeth T., To, William W. K., Leung, Wing C., Tang, Rebecca Y. K., Au-Yeung, Sidney K. C., Lam, Helena, Kung, Yu Y., Zhang, Xiuqing, van Vugt, John M. G., Minekawa, Ryoko, Tang, Mary H. Y., Wang, Jun, Oudejans, Cees B. M., Lau, Tze K., Nicolaides, Kypros H., Lo, Y. M. Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130771/
https://ncbi.nlm.nih.gov/pubmed/21755002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021791
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