Recruited Cells Can Become Transformed and Overtake PDGF-Induced Murine Gliomas In Vivo during Tumor Progression

BACKGROUND: Gliomas are thought to form by clonal expansion from a single cell-of-origin, and progression-associated mutations to occur in its progeny cells. Glioma progression is associated with elevated growth factor signaling and loss of function of tumor suppressors Ink4a, Arf and Pten. Yet, gli...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fomchenko, Elena I., Dougherty, Joseph D., Helmy, Karim Y., Katz, Amanda M., Pietras, Alexander, Brennan, Cameron, Huse, Jason T., Milosevic, Ana, Holland, Eric C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130733/
https://ncbi.nlm.nih.gov/pubmed/21754979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020605
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados