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VennVax, a DNA-prime, peptide-boost multi-T-cell epitope poxvirus vaccine, induces protective immunity against vaccinia infection by T cell response alone

The potential for smallpox to be disseminated in a bioterror attack has prompted development of new, safer smallpox vaccination strategies. We designed and evaluated immunogenicity and efficacy of a T-cell epitope vaccine based on conserved and antigenic vaccinia/variola sequences, identified using...

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Detalles Bibliográficos
Main Authors: Moise, Leonard, Buller, R. Mark, Schriewer, Jill, Lee, Jinhee, Frey, Sharon, Martin, William, De Groot, Anne S.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130609/
https://ncbi.nlm.nih.gov/pubmed/21055490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.10.064
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