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Alternative splicing and genetic diversity: silencers are more frequently modified by SNVs associated with alternative exon/intron borders

With the availability of a large amount of genomic data it is expected that the influence of single nucleotide variations (SNVs) in many biological phenomena will be elucidated. Here, we approached the problem of how SNVs affect alternative splicing. First, we observed that SNVs and exonic splicing...

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Détails bibliographiques
Auteurs principaux: de Souza, Jorge E. S., Ramalho, Rodrigo F., Galante, Pedro A. F., Meyer, Diogo, de Souza, Sandro J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130264/
https://ncbi.nlm.nih.gov/pubmed/21398627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr081
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