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Alternative splicing and genetic diversity: silencers are more frequently modified by SNVs associated with alternative exon/intron borders

With the availability of a large amount of genomic data it is expected that the influence of single nucleotide variations (SNVs) in many biological phenomena will be elucidated. Here, we approached the problem of how SNVs affect alternative splicing. First, we observed that SNVs and exonic splicing...

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Detalhes bibliográficos
Main Authors: de Souza, Jorge E. S., Ramalho, Rodrigo F., Galante, Pedro A. F., Meyer, Diogo, de Souza, Sandro J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130264/
https://ncbi.nlm.nih.gov/pubmed/21398627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr081
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