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Rapid binding and release of Hfq from ternary complexes during RNA annealing

The Sm protein Hfq binds small non-coding RNA (sRNAs) in bacteria and facilitates their base pairing with mRNA targets. Molecular beacons and a 16 nt RNA derived from the Hfq binding site in DsrA sRNA were used to investigate how Hfq accelerates base pairing between complementary strands of RNA. Sto...

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Bibliografiske detaljer
Main Authors: Hopkins, Julia F., Panja, Subrata, Woodson, Sarah A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130257/
https://ncbi.nlm.nih.gov/pubmed/21378124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr062
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