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GPHMM: an integrated hidden Markov model for identification of copy number alteration and loss of heterozygosity in complex tumor samples using whole genome SNP arrays

There is an increasing interest in using single nucleotide polymorphism (SNP) genotyping arrays for profiling chromosomal rearrangements in tumors, as they allow simultaneous detection of copy number and loss of heterozygosity with high resolution. Critical issues such as signal baseline shift due t...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Li, Ao, Liu, Zongzhi, Lezon-Geyda, Kimberly, Sarkar, Sudipa, Lannin, Donald, Schulz, Vincent, Krop, Ian, Winer, Eric, Harris, Lyndsay, Tuck, David
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130254/
https://ncbi.nlm.nih.gov/pubmed/21398628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr014
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