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Critical molecular pathways in cancer stem cells of chronic myeloid leukemia

Inhibition of BCR-ABL with kinase inhibitors in the treatment of Philadelphia-positive (Ph(+)) chronic myeloid leukemia (CML) is highly effective in controlling but not curing the disease. This is largely due to the inability of these kinase inhibitors to kill leukemia stem cells (LSCs) responsible...

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Autors principals: Chen, Yaoyu, Peng, Cong, Sullivan, Con, Li, Dongguang, Li, Shaoguang
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130198/
https://ncbi.nlm.nih.gov/pubmed/20574455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2010.143
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