Elevation of Intracellular Calcium in Clonal Neuronal and Embryonic Kidney Cells Involves Endogenous Endothelin-A Receptors Linked to Phospholipase C Through Gα(q/11)

Endothelin-1 (ET-1) is a pain mediator, elevated in skin after injury, which potentiates noxious thermal and mechanical stimuli (hyperalgesia) through the activation of ET(A) (and, perhaps, ET(B)) receptors on pain fibers. Part of the mechanism underlying this effect has recently been shown to invol...

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Bibliographic Details
Main Authors: Montmayeur, Jean-Pierre, Barr, Travis P., Kam, Sarah A., Packer, Samuel J., Strichartz, Gary R.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130094/
https://ncbi.nlm.nih.gov/pubmed/21515378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2011.04.003
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