A Novel Lung Disease Phenotype Adjusted for Mortality Attrition for Cystic Fibrosis Genetic Modifier Studies

Genetic studies of lung disease in Cystic Fibrosis are hampered by the lack of a severity measure that accounts for chronic disease progression and mortality attrition. Further, combining analyses across studies requires common phenotypes that are robust to study design and patient ascertainment. Us...

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Autors principals: Taylor, Chelsea, Commander, Clayton W., Collaco, Joseph M., Strug, Lisa J., Li, Weili, Wright, Fred A., Webel, Aaron D., Pace, Rhonda G., Stonebraker, Jaclyn R., Naughton, Kathleen, Dorfman, Ruslan, Sandford, Andrew, Blackman, Scott M., Berthiaume, Yves, Paré, Peter, Drumm, Mitchell L., Zielenski, Julian, Durie, Peter, Cutting, Garry R., Knowles, Michael R., Corey, Mary
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130075/
https://ncbi.nlm.nih.gov/pubmed/21462361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ppul.21456
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