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Both the C-Terminal Polylysine Region and the Farnesylation of K-RasB Are Important for Its Specific Interaction with Calmodulin

BACKGROUND: Ras protein, as one of intracellular signal switches, plays various roles in several cell activities such as differentiation and proliferation. There is considerable evidence showing that calmodulin (CaM) binds to K-RasB and dissociates K-RasB from membrane and that the inactivation of C...

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Detalhes bibliográficos
Main Authors: Wu, Ling-Jia, Xu, Li-Rong, Liao, Jun-Ming, Chen, Jie, Liang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130059/
https://ncbi.nlm.nih.gov/pubmed/21750741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021929
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