Suppression of Allograft Rejection by Tim-1-Fc through Cross-Linking with a Novel Tim-1 Binding Partner on T Cells

Engagement of T-cell immunoglobulin mucin (Tim)-1 on T cells with its ligand, Tim-4, on antigen presenting cells delivers positive costimulatory signals to T cells. However, the molecular mechanisms for Tim-1-mediated regulation of T-cell activation and differentiation are relatively poorly understo...

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Detalhes bibliográficos
Main Authors: Xiao, Liang, Fu, Zhi-ren, Liu, Fang, Zhang, Lu-ding, Shi, Xiao-min, Shen, Xiao-yun, Ni, Zhi-jia, Fu, Hong, Li, Rui-dong, Cao, Xue-tao, Ding, Guo-shan, Wang, Quan-xing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130052/
https://ncbi.nlm.nih.gov/pubmed/21750723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021697
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