The Polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo

Many developmental control genes contain paused RNA Polymerase II (Pol II) and are thereby “poised” for rapid and synchronous activation in the early Drosophila embryo. Evidence is presented that Polycomb group (PcG) repressors can influence paused Pol II. ChIP-Seq and GRO-Seq assays were used to de...

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Bibliographic Details
Main Authors: Chopra, Vivek S., Hendrix, David A., Core, Leighton J., Tsui, Chiahao, Lis, John T., Levine, Michael
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130001/
https://ncbi.nlm.nih.gov/pubmed/21700228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.05.009
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