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sGCα(1) mediates the negative inotropic effects of NO in cardiac myocytes independent of changes in calcium handling
In the heart, nitric oxide (NO) modulates contractile function; however, the mechanisms responsible for this effect are incompletely understood. NO can elicit effects via a variety of mechanisms including S-nitrosylation and stimulation of cGMP synthesis by soluble guanylate cyclase (sGC). sGC is a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129918/ https://ncbi.nlm.nih.gov/pubmed/21536853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01273.2010 |
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