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Flow-dependent Smad2 phosphorylation and TGIF nuclear localization in human aortic endothelial cells

Endothelial cells respond to fluid flow stimulation through transient and sustained signal pathway activation. Smad2 is a signaling molecule and transcription factor in the Smad signaling pathway, traditionally associated with TGF-β. Although phosphorylation of Smad2 in the receptor-dependent COOH-t...

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Detalhes bibliográficos
Main Authors: Shepherd, Robert D., Kos, Stephanie M., Rinker, Kristina D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129916/
https://ncbi.nlm.nih.gov/pubmed/21490324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00668.2010
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