Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses

Cardiac fibroblasts play a key role in fibrosis development in response to stress and injury. Angiotensin II (ANG II) is a major profibrotic activator whose downstream effects (such as phospholipase Cβ activation, cell proliferation, and extracellular matrix secretion) are mainly mediated via G(q)-c...

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Detalhes bibliográficos
Main Authors: Zhang, Peng, Su, Jialin, King, Michelle E., Maldonado, Angel E., Park, Cindy, Mende, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Signaling and Stress Response
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129912/
https://ncbi.nlm.nih.gov/pubmed/21498776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00026.2011
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