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Protein kinase C-ε activation induces mitochondrial dysfunction and fragmentation in renal proximal tubules

PKC-ε activation mediates protection from ischemia-reperfusion injury in the myocardium. Mitochondria are a subcellular target of these protective mechanisms of PKC-ε. Previously, we have shown that PKC-ε activation is involved in mitochondrial dysfunction in oxidant-injured renal proximal tubular c...

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Main Authors: Nowak, Grazyna, Bakajsova, Diana, Samarel, Allen M.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129894/
https://ncbi.nlm.nih.gov/pubmed/21289057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00364.2010
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