Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity

The neural cell adhesion molecule, NCAM, is a pivotal regulator of neural development, with key roles in axonal and dendritic growth and synaptic plasticity. Alterations in NCAM expression or proteolytic cleavage have been linked to human neuropsychiatric disorders such as schizophrenia, bipolar dis...

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Hauptverfasser: Brennaman, Leann H., Kochlamazashvili, Gaga, Stoenica, Luminita, Nonneman, Randall J., Moy, Sheryl S., Schachner, Melitta, Dityatev, Alexander, Maness, Patricia F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129860/
https://ncbi.nlm.nih.gov/pubmed/21515372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.008
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