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Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity
The neural cell adhesion molecule, NCAM, is a pivotal regulator of neural development, with key roles in axonal and dendritic growth and synaptic plasticity. Alterations in NCAM expression or proteolytic cleavage have been linked to human neuropsychiatric disorders such as schizophrenia, bipolar dis...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129860/ https://ncbi.nlm.nih.gov/pubmed/21515372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2011.04.008 |
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