hMSC-mediated Concurrent Delivery of Endostatin and Carboxylesterase to Mouse Xenografts Suppresses Glioma Initiation and Recurrence

Glioma stem cells (GSCs) are known to be maintained within a “vascular niche” thereby, disruption of this microenvironment using antiangiogenesis agents is a promising therapeutic modality. However, this regimen leads to treatment failure and tumor recurrence in patients with glioblastoma multiforme...

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Bibliographische Detailangaben
Hauptverfasser: Yin, Jinlong, Kim, Jun-Kyum, Moon, Jai-Hee, Beck, Samuel, Piao, Dachuan, Jin, Xun, Kim, Sung-Hak, Lim, Young Chang, Nam, Do-Hyun, You, Seungkwon, Kim, Hyunggee, Choi, Yun-Jaie
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129799/
https://ncbi.nlm.nih.gov/pubmed/21386822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.28
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