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Cancer cells’ epigenetic composition and predisposition to histone deacetylase inhibitor sensitization

Normal cells are up to ten times more resistant to histone deacetylase inhibitors (HDACis)-induced cell death compared with transformed cells. The molecular processes underlying this selectivity for cancer cells are still not well understood. Although a differential response to oxidative stress and...

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Hlavní autoři: Nalabothula, Narasimharao, Carrier, France
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129700/
https://ncbi.nlm.nih.gov/pubmed/21743813
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