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hzAnalyzer: detection, quantification, and visualization of contiguous homozygosity in high-density genotyping datasets
The analysis of contiguous homozygosity (runs of homozygous loci) in human genotyping datasets is critical in the search for causal disease variants in monogenic disorders, studies of population history and the identification of targets of natural selection. Here, we report methods for extracting ho...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129671/ https://ncbi.nlm.nih.gov/pubmed/21396103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-3-r21 |
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