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Linkage disequilibrium of evolutionarily conserved regions in the human genome

BACKGROUND: The strong linkage disequilibrium (LD) recently found in genic or exonic regions of the human genome demonstrated that LD can be increased by evolutionary mechanisms that select for functionally important loci. This suggests that LD might be stronger in regions conserved among species th...

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Detalhes bibliográficos
Main Authors: Kato, Mamoru, Sekine, Akihiro, Ohnishi, Yozo, Johnson, Todd A, Tanaka, Toshihiro, Nakamura, Yusuke, Tsunoda, Tatsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1769491/
https://ncbi.nlm.nih.gov/pubmed/17192199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-7-326
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