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Evaluation of (99m)Technetium-Mebrofenin and (99m)Technetium-Sestamibi as Specific Probes for Hepatic Transport Protein Function in Rat and Human Hepatocytes
PURPOSE: This study characterized (99m)Tc-Mebrofenin (MEB) and (99m)Tc-Sestamibi (MIBI) hepatic transport and preferential efflux routes (canalicular vs. basolateral) in rat and human sandwich-cultured hepatocytes (SCH). METHODS: (99m)Tc-MEB and (99m)Tc-MIBI disposition was determined in suspended h...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129651/ https://ncbi.nlm.nih.gov/pubmed/20652625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0203-x |
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