SCHWANNOMIN/MERLIN PROMOTES SCHWANN CELL ELONGATION AND INFLUENCES MYELIN SEGMENT LENGTH

The Neurofibromatosis type 2 tumor suppressor, schwannomin (Sch) is a plasma membrane-cytoskeleton linking protein that regulates receptor signaling and actin dynamics. We examined Sch’s role in specifying morphological changes needed for Schwann cell (SC) function in vitro. Isolated Sch-GFP-express...

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Autores principales: Thaxton, Courtney, Bott, Marga, Walker, Barbara, Sparrow, Nicklaus A., Lambert, Stephen, Fernandez-Valle, Cristina
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129596/
https://ncbi.nlm.nih.gov/pubmed/21182951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2010.12.006
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