Pharmacological Characterization of Chemically Synthesized Monomeric phi29 pRNA Nanoparticles for Systemic Delivery

Previous studies have shown that the packaging RNA (pRNA) of bacteriophage phi29 DNA packaging motor folds into a compact structure, constituting a RNA nanoparticle that can be modularized with functional groups as a nanodelivery system. pRNA nanoparticles can also be self-assembled by the bipartite...

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Detalhes bibliográficos
Main Authors: Abdelmawla, Sherine, Guo, Songchuan, Zhang, Limin, Pulukuri, Sai M, Patankar, Prithviraj, Conley, Patrick, Trebley, Joseph, Guo, Peixuan, Li, Qi-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129564/
https://ncbi.nlm.nih.gov/pubmed/21468004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.35
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