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Specific Delivery of Therapeutic RNAs to Cancer Cells via the Dimerization Mechanism of phi29 Motor pRNA

The application of small RNA in therapy has been hindered by the lack of an efficient and safe delivery system to target specific cells. Packaging RNA (pRNA), part of the DNA-packaging motor of bacteriophage phi29(φ29), was manipulated by RNA nanotechnology to make chimeric RNAs that form dimers via...

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Bibliografski detalji
Glavni autori: GUO, SONGCHUAN, TSCHAMMER, NUSKA, MOHAMMED, SULMA, GUO, PEIXUAN
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837361/
https://ncbi.nlm.nih.gov/pubmed/16149908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2005.16.1097
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