TLR9 and the NLRP3 Inflammasome Link Acinar Cell Death With Inflammation in Acute Pancreatitis

BACKGROUND & AIMS: Acute pancreatitis is characterized by early activation of intracellular proteases followed by acinar cell death and inflammation. Activation of damage-associated molecular pattern (DAMP) receptors and a cytosolic complex termed the inflammasome initiates forms of inflammation...

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Detalhes bibliográficos
Main Authors: Hoque, Rafaz, Sohail, Muhammad, Malik, Ahsan, Sarwar, Sherhayar, Luo, Yuhuan, Shah, Ahsan, Barrat, Franck, Flavell, Richard, Gorelick, Fred, Husain, Sohail, Mehal, Wajahat
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129497/
https://ncbi.nlm.nih.gov/pubmed/21439959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.03.041
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