Quantitative fluorescence in intracranial tumor: implications for ALA-induced PpIX as an intraoperative biomarker

OBJECT: Accurate discrimination between tumor and normal tissue is crucial for optimal tumor resection. Qualitative fluorescence of protoporphyrin IX (PpIX), synthesized endogenously following δ-aminolevulinic acid (ALA) administration, has been used for this purpose in high-grade glioma (HGG). The...

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Autors principals: Valdés, Pablo A., Leblond, Frederic, Kim, Anthony, Harris, Brent T., Wilson, Brian C., Fan, Xiaoyao, Tosteson, Tor D., Hartov, Alex, Ji, Songbai, Erkmen, Kadir, Simmons, Nathan E., Paulsen, Keith D., Roberts, David W.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129387/
https://ncbi.nlm.nih.gov/pubmed/21438658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2011.2.JNS101451
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