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Selective accumulation of ALA-induced PpIX and photodynamic effect in chemically induced hepatocellular carcinoma

The possibility of 5-aminolaevulinic acid-based photodynamic therapy (ALA-PDT) for liver cancer was investigated using a chemically induced hepatocellular carcinoma (HCC) model. Endogenously synthesised protoporphyrin IX (PpIX) following the administration of ALA is an effective photosensitiser for...

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Autori principali: Otake, M, Nishiwaki, M, Kobayashi, Y, Baba, S, Kohno, E, Kawasaki, T, Fujise, Y, Nakamura, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2376916/
https://ncbi.nlm.nih.gov/pubmed/12915887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601135
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