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Blood-brain barrier disruption and vascular damage induced by ultrasound bursts combined with microbubbles can be influenced by choice of anesthesia protocol

Numerous animal studies have demonstrated that ultrasound bursts combined with a microbubble-based ultrasound contrast agent can temporarily disrupt the blood-brain barrier (BBB) with little or no other apparent effects to the brain. As the BBB is a primary limitation to the use of most drugs in the...

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Autors principals: McDannold, Nathan, Zhang, Yongzhi, Vykhodtseva, Natalia
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129385/
https://ncbi.nlm.nih.gov/pubmed/21645965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultrasmedbio.2011.04.019
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