Intraflagellar transport delivers tubulin isotypes to sensory cilium middle and distal segments

Sensory cilia are assembled and maintained by kinesin-2-dependent intraflagellar transport (IFT). We investigated if two C. elegans α- and β-tubulin isotypes, identified via mutants that lack their cilium distal segments, are delivered to their assembly sites by IFT. Mutations in conserved residues...

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Main Authors: Hao, Limin, Thein, Melanie, Brust-Mascher, Ingrid, Civelekoglu-Scholey, Gul, Lu, Yun, Acar, Seyda, Prevo, Bram, Shaham, Shai, Scholey, Jonathan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129367/
https://ncbi.nlm.nih.gov/pubmed/21642982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2268
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