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Adenosine Induces Loss of Actin Stress Fibers and Inhibits Contraction in Hepatic Stellate Cells via Rho Inhibition

The Rho/ROCK pathway is activated in differentiated hepatic stellate cells (HSCs) and is necessary for assembly of actin stress fibers, contractility, and chemotaxis. Despite the importance of this pathway in HSC biology, physiological inhibitors of the Rho/ROCK pathway in HSCs are not known. We dem...

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Detaylı Bibliyografya
Asıl Yazarlar: Sohail, Muhammad A., Hashmi, Ardeshir Z., Hakim, Wyel, Watanabe, Azuma, Zipprich, Alexander, Groszmann, Roberto J., Dranoff, Jonathan A., Torok, Natalie J., Mehal, Wajahat Z.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129263/
https://ncbi.nlm.nih.gov/pubmed/18844235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22589
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