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Detection of common single nucleotide polymorphisms synthesizing quantitative trait association of rarer causal variants
Genome-wide association (GWA) studies have identified hundreds of common (minor allele frequency ≥5%) single nucleotide polymorphisms (SNPs) associated with phenotype traits or diseases, yet causal variants accounting for the association signals have rarely been determined. A question then raised is...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129254/ https://ncbi.nlm.nih.gov/pubmed/21441355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.115832.110 |
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