Wird geladen...

Enhanced Biosynthesis of Coagulation Factor VIII through Diminished Engagement of the Unfolded Protein Response

Human and porcine coagulation factor VIII (fVIII) display a biosynthetic efficiency differential that is being exploited for the development of new protein and gene transfer-based therapies for hemophilia A. The cellular and/or molecular mechanism(s) responsible for this phenomenon have yet to be un...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Brown, Harrison C., Gangadharan, Bagirath, Doering, Christopher B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129224/
https://ncbi.nlm.nih.gov/pubmed/21606503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238758
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!