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Transautocrine Signaling by Membrane Neuregulins Requires Cell Surface Targeting, Which Is Controlled by Multiple Domains

The neuregulins (NRGs) play important roles in animal development and homeostasis, and their deregulation has been linked to diseases such as cancer and schizophrenia. The NRGs belong to the epidermal growth factor (EGF) family of transmembrane growth factors. Although NRGs may be synthesized as tra...

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Detalhes bibliográficos
Main Authors: Montero, Juan Carlos, Rodríguez-Barrueco, Ruth, Pandiella, Atanasio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129214/
https://ncbi.nlm.nih.gov/pubmed/21572038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190835
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