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Heat shock activates the I-κBα promoter and increases I-κBα mRNA expression
Recent data indicate that the heat shock response inhibits nuclear translocation of the proinflammatory transcription factor NF-κB. Under basal conditions NF-κB is retained in the cytoplasm by an inhibitory protein called I-κB which exists as two major isoforms: I-κBα and I-κBβ. Induction of the hea...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cell Stress Society International
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312912/ https://ncbi.nlm.nih.gov/pubmed/10467103 |
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