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Heat shock activates the I-κBα promoter and increases I-κBα mRNA expression

Recent data indicate that the heat shock response inhibits nuclear translocation of the proinflammatory transcription factor NF-κB. Under basal conditions NF-κB is retained in the cytoplasm by an inhibitory protein called I-κB which exists as two major isoforms: I-κBα and I-κBβ. Induction of the hea...

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Detalles Bibliográficos
Main Authors: Wong, Hector R., Ryan, Marnie A., Menendez, Ingrid Y., Wispé, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Stress Society International 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC312912/
https://ncbi.nlm.nih.gov/pubmed/10467103
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