Enhanced protein denaturation in indomethacin-treated cells

Abstract Indomethacin, a potent anti-inflammatory drug, activates the DNA-binding activity of human heat shock transcription factor 1 (HSF1), but this is insufficient to elevate heat shock gene expression. However, indomethacin pretreatment leads to a complete heat shock response at temperatures tha...

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Detalhes bibliográficos

Publicado no:	Cell Stress Chaperones
Principais autores:	Roussou, Irene, Trung Nguyen, Van, Pagoulatos, Gerassimos N., Bensaude, Olivier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2000
Assuntos:	Short Communications
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10701834/ https://ncbi.nlm.nih.govhttps://doi.org/10.1043/1355-8145(2000)005<0008:EPDIIT>2.0.CO;2
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