Enhanced protein denaturation in indomethacin-treated cells
Abstract Indomethacin, a potent anti-inflammatory drug, activates the DNA-binding activity of human heat shock transcription factor 1 (HSF1), but this is insufficient to elevate heat shock gene expression. However, indomethacin pretreatment leads to a complete heat shock response at temperatures tha...
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| Опубликовано в:: | Cell Stress Chaperones |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2000
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10701834/ https://ncbi.nlm.nih.govhttps://doi.org/10.1043/1355-8145(2000)005<0008:EPDIIT>2.0.CO;2 |
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