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Analysis of the T cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors
A significant enrichment of CD4(+)Foxp3(+) T cells (Tregs) is frequently observed in murine and human carcinomas. As Tregs can limit effective anti-tumor immune responses, thereby promoting tumor progression, it is important that the mechanisms underpinning intra-tumoral accumulation of Tregs are id...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128990/ https://ncbi.nlm.nih.gov/pubmed/21156649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1797 |
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