HSP70 and heat shock factor 1 cooperate to repress Ras-induced transcriptional activation of the c-fos gene

Heat shock protein 70 (HSP70) is a molecular chaperone involved in protein folding and resistance to the deleterious effects of stress. Here we show that HSP70 suppresses transcription of c-fos, an early response gene that is a key component of the ubiquitous AP-1 transcription factor complex. HSP70...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: He, Haiying, Chen, Changmin, Xie, Yue, Asea, Alexzander, Calderwood, Stuart K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2000
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312869/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11189444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1379/1466-1268(2000)005<0406:hahsfc>2.0.co;2
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