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Pigtailed Macaque Model Refinement: Topical Microbicide Safety in the Presence of Coitus
BACKGROUND: Inclusion of sexual activity in the macaque model for topical microbicide safety evaluation would more closely mimic human use of topical microbicides and provide a more rigorous safety assessment. METHODS: Initially male-female partners were monitored in co-housing arrangements to deter...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128681/ https://ncbi.nlm.nih.gov/pubmed/21443565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2011.00478.x |
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