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Pigtailed Macaque Model Refinement: Topical Microbicide Safety in the Presence of Coitus

BACKGROUND: Inclusion of sexual activity in the macaque model for topical microbicide safety evaluation would more closely mimic human use of topical microbicides and provide a more rigorous safety assessment. METHODS: Initially male-female partners were monitored in co-housing arrangements to deter...

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Detalhes bibliográficos
Main Authors: Cosgrove Sweeney, Yvonne T, Angeles, Ray O, Cummings, Peter K, Smith, April D, Patton, Dorothy L
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128681/
https://ncbi.nlm.nih.gov/pubmed/21443565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0684.2011.00478.x
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